Dagmar Wachten

Gaucher disease and the Sphinx

Sphingosine inhibits the enzyme GBA2, thereby regulating the degradation of lipid-sugar compounds in cells.

Sphingosine, a compound as enigmatic as the sphinx, plays a key role in the metabolic disorder Gaucher disease. Scientists from the Bonn research center caesar have identified some of the complex molecular mechanisms of how the disease develops. These findings were published in the Journal of Biological Chemistry (JBC) and could contribute to the development of new therapies in the future.